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Cholesterol analogs modulate lipid nanoparticle performance for mRNA delivery after lyophilization and enable ocular disease therapy

Authors: Ting Wang, Wanqi Li, Jianyang Chen, Sitian Cheng, Min Gao, Chengyu Jiang, Chengyu Jiang, Bingyi Hu, Tzu-Cheng Sung, Akon Higuchi

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.103044

Products & Services: Custom mRNA synthesis

NIR-II Biomimetic Nanoplatform Optogenetic CD274 Editing of HNSCC Immunogenicity for Enhanced Photoimmunotherapy

Authors: Yang Chen, Longcai Liu, Xiaojuan Hu, Yilin Huang, Shijie Yao, Lichen Ji, Hai Zou, Xiaozhou Mou, Yu Cai

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.102803

Products & Services: Synthetic Guide RNA CRISPR Plasmids

Structural and functional dissection of a higherorder oligomerization interface in yeast ceramide synthase

Authors: Qi Fang, Chang Yang, Nan Yao, Tian Xie, Xin Gong

Journal: nature communications

PubMed ID: 41917020

Doi: doi.org/10.1038/s41467-026-71272-8

Products & Services: Protein and Antibody Isolation

Oriented nanobody–field-effect transistor interfaces enable ultrasensitive cancer biomarker detection

Authors: Zhicheng Zhang, Duanlian Ye, Yuxuan Li, Guannan Li, Yanbo Jing, Jun Dai, Quan Wang, Tao Liu, Fan Xia, Xiaoding Lou

Journal: nature sensors

Doi: 10.1038/s44460-026-00040-4

Products & Services: Gene Synthesis

Chemically Synthesized H3K14Ub Unveils Clr4's IDR-Mediated Multivalent Nucleosome Recognition in H3K9 Methylation

Authors: Maoshen Sun, Yunxiang Du, Zhengqing Li, Akejiang Aderjiang, Meixuan Xin, Huasong Ai

Journal: ANGEWANDTE CHEMIE International Edition

PubMed ID: 41873495

Doi: 10.1002/anie.202520817

Products & Services: Gene Synthesis

Y-shaped nanoprobe-based DNA microarray for rapid detection of multiplex miRNAs with single-nucleotide specificity

Authors: Yichen Du, Rui Sun, Shuang Hao, Fuwan Yang, Qifei Hu, Ruyan Xue

Journal: Microchemical Journal

Doi: 10.1016/j.microc.2026.117169

Products & Services: Custom DNA/RNA Oligos

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Authors: Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu

Journal: Advanced Science

PubMed ID: 41787915

Doi: 10.1002/advs.202520157

Products & Services: Protein Electrophoresis and Western

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagy

Authors: Yan Wang, Fei Xu, Chengxiang Song, Xi Wang, Hao Zhou, Tianyi Qu, Hongde Li, Qiang Luo, Wenhua Lei, Yue Yin, Fangyang Huang, Mao Chen

Journal: Signal transduction and targeted therapy

PubMed ID: 41820291

Doi: 10.1038/s41392-026-02624-5

Products & Services: Custom mRNA synthesis