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Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis

Authors: Chia-Ming Chang, Kuang-Hua Cheng, Tsai-Yin Wei, Meng-Ping Lu, Yi-Chen Chen, Yen-Ta Lu

Journal: J Immunol

PubMed ID: 36961438

Doi: 10.4049/jimmunol.2200222

Products & Services: Proteins, Expression, Isolation and Analysis

Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM

Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb

Journal: Biochemistry

PubMed ID: 37188334

Doi: 10.1021/acs.biochem.3c00150

Products & Services: Proteins, Expression, Isolation and Analysis

Antibody blockade of Jagged1 attenuates choroidal neovascularization

Authors: Torleif Tollefsrud Gjølberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Panagiotis F Christopoulos, Malin Bern, Stian Foss, Goran Petrovski, Morten C Moe, Guttorm Haraldsen, Johanna Hol Fosse, Bjørn Steen Skålhegg, Jan Terje Andersen, Eirik Sundlisæter

Journal: Nat Commun

PubMed ID: 37253747

Doi: 10.1038/s41467-023-38563-w

Products & Services: Proteins, Expression, Isolation and Analysis

Design and development of microformulations for rapid release of small molecules and oligonucleotides

Authors: T Brown, M Stanton, F Cros, S Cho, A Kiselyov

Journal: Eur J Pharm Sci

PubMed ID: 37220816

Doi: 10.1016/j.ejps.2023.106472

Products & Services: Proteins, Expression, Isolation and Analysis

Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core

Authors: Pantelis Poumbourios, Christine Langer, Irene Boo, Tasnim Zakir, Rob J Center, Anouschka Akerman, Vanessa Milogiannakis, Anupriya Aggarwal, Bronte A Johnstone, Jungmin Ha, Fasséli Coulibaly, Stuart G Turville, Heidi E Drummer

Journal: PLoS Pathog

PubMed ID: 37200378

Doi: 10.1371/journal.ppat.1010981

Products & Services: Proteins, Expression, Isolation and Analysis

Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in knock-out mammalian cells

Authors: Gábor Tax, Kevin P Guay, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Snežana Vasiljević, Andrea Lia, Carlos P Modenutti, Kees R Straatman, Angelo Santino, Maurizio Molinari, Nicole Zitzmann, Daniel N Hebert, Pietro Roversi, Marco Trerotola

Journal: biorxiv

PubMed ID: 37398215

Doi: 10.1101/2023.05.30.542711

Products & Services: Proteins, Expression, Isolation and Analysis

The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis

Authors: Jennilee M Davidson, Sharlynn S L Wu, Stephanie L Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L Williams, Marco Morsch, Ian P Blair, Antonio Di Ieva, Shu Yang, Roger S Chung, Albert Lee

Journal: Mol Neurobiol

PubMed ID: 37243816

Doi: 10.1007/s12035-023-03355-2

Products & Services: Proteins, Expression, Isolation and Analysis

saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern

Authors: Mai Komori, Takuto Nogimori, Amber L Morey, Takashi Sekida, Keiko Ishimoto, Matthew R Hassett, Yuji Masuta, Hirotaka Ode, Tomokazu Tamura, Rigel Suzuki, Jeff Alexander, Yasutoshi Kido, Kenta Matsuda, Takasuke Fukuhara, Yasumasa Iwatani, Takuya Yamamoto, Jonathan F Smith, Wataru Akahata

Journal: Nat Commun

PubMed ID: 37208330

Doi: 10.1038/s41467-023-38457-x

Products & Services: Proteins, Expression, Isolation and Analysis

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response

Authors: Shridhar Bale, Lifei Yang, Mehrdad Alirezaei, Richard Wilson, Takayuki Ota, Esmeralda D Doyle, Christopher A Cottrell, Javier Guenaga, Karen Tran, Wenjuan Li, Leonidas Stamatatos, David Nemazee, Andrew B Ward, Richard T Wyatt

Journal: Front Immunol

PubMed ID: 37283743

Doi: 10.3389/fimmu.2023.1180959

Products & Services: Proteins, Expression, Isolation and Analysis

CFTR and dystrophin encoding plasmids carrying both luciferase reporter gene, nuclear import specific sequences and triple helix sites

Authors: Delphine Maze, Caroline Girardin, Nathalie Benz, Tristan Montier, Chantal Pichon, Patrick Midoux

Journal: Plasmid

PubMed ID: 37207938

Doi: 10.1016/j.plasmid.2023.102686

Products & Services: Proteins, Expression, Isolation and Analysis