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目录产品 » CD19, His, Cynomolgus/Rhesus macaque

CD19, His, Cynomolgus/Rhesus macaque

CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.
￥3500
 Z04141-100

Species Cynomolgus/Rhesus macaque
Protein Construction
CD19 (Gln21-Trp291)
Accession # A0A2K5W8L9		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Loaded Anti­-CD19 Antibody, hFc Tag on ProA­-Biosensor can bind CD19, His, Cynomolgus/Rhesus macaque in BLI assay (Gator® Prime). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 30.96 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CD19, His, Cynomolgus/Rhesus Macaque

CD19, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

CD19, His, Cynomolgus/Rhesus Macaque

Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind CD19, His, Cynomolgus/Rhesus macaque with an affinity constant of 0.46 μM as determined in SPR assay (Biacore T200). »

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Target Background CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.
Synonyms CD19; B4; CVID3; Leu-12; MGC12802
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 For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.