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目录产品 » Her2, Avi & His, Human

Her2, Avi & His, Human

ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane.
￥3300 在线订购包邮(港澳台除外)
 Z03806-100

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Species Human
Protein Construction
Her2 (Thr23-Thr652)
Accession # P04626-1		 His tag Avi tag
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized Her2, Avi & His, Human (Cat.No.: Z03806) at 0.5 μg/ml can bind Anti-Her2 Antibody.
Expression System HEK293
Theoretical Molecular Weight 72.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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Her2, Avi & His, Human

Her2, Avi & His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Her2, Avi & His, Human

The purity of Her2, Avi & His, Human is greater than 95% as determined by SEC-HPLC. »

Her2, Avi & His, Human

Immobilized Her2, Avi & His, Human at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER2 Antibody, hFc Tag with the EC50 of 7.4 ng/ml determined by ELISA. »

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Target Background ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane.
Synonyms EGFR2; ErbB2; HER2; HER-2; TKR1; ERBB2;
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 For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.